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Some people are affected more than others. Radiation therapy uses high-powered beams, such as X-rays and protons, to kill cancer cells. Amin MB, et al. Our main strength was our use of nation-wide registries allowing complete follow-up for the competing outcomes of death and colostomy. A modified staging system based on ultrasound findings has been proposed:
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The colostomy rate is considered a relevant end point in anal cancer because it captures both locoregional failure and toxicity compromising anal sphincter preservation. Living with a colostomy will require a modification of your lifestyle. During the study period, oncologic treatment of anal cancer in Denmark took place in six public hospitals, of which four were included in our study. The cumulative incidences of tumor-related colostomy, therapy-related colostomy, and death are shown in Figure 1. We included patients with anal cancer.
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